Cambridge Healthtech Institute's Second Annual

Microbial Production

( 微生物表现 )

Optimizing the Production of Microbial-Based Expression Systems

2018年1月11日 - 12日 | Hilton San Diego Bayfront | San Diego, CA

 

Microbial expression systems offer significant advantages over other hosts by providing faster development times, greater yields, lower production costs, particularly in E. coli which is one of the most widely used hosts for protein production. However, limitations around glycosylation and central metabolic pathways poses significant challenges.

Cambridge Healthtech Institute's Microbial Production conference covers the latest developments in microbial expression and production - from host strain development to metabolic engineering, assembly to scale-up, downstream processing to potential aggregation - with particular focus on the role of E. coli for biotherapeutics, novel products and other industrial applications.

We invite presentation proposals on the following preliminary topics:

  • Optimizing microbial expression systems
  • Designing glycosylation and other PTMs into E. coli systems
  • Developing new microbial production strains
  • Novel metabolic pathways
  • Scaling up microbial processes
  • Disposable technologies for microbial production
  • Efficient expression and assembly of full-length antibodies
  • Use of Shuffle to express IgGs
  • Recovery and Purification challenges - column limitations
  • High throughput technologies
  • Protein folding, Aggregation
  • Concerns around degradation
  • Dealing with endotoxins
  • Engineering microbes to produce novel products

* 活动内容有可能不事先告知作更动及调整。