Cambridge Healthtech Institute's Seventh Annual

Bispecific Antibody Therapeutics

( 双特异性抗体疗法 )

Engineering Multi-Specificity

2018年1月11日 - 12日


CHI's Bispecific Antibody Therapeutics conference explores the challenges of engineering multi-specificity to achieve more effective therapies that bind to at least two molecular targets simultaneously. These next-generation antibody formats are showing efficacy in the efforts to conquer cancer and other diseases. Case studies will highlight novel engineering approaches that address safety, stability, enhanced targeting, and manufacturability, as the conference examines current developments, and future directions for these promising molecules.

We invite presentation proposals on the following preliminary topics:

  • Case studies
  • Pre-Clinical & clinical data
  • Cancer
  • Antitumor activity
  • Tumor specific antigens (TSAs)
  • Stability
  • Crossing the Blood-Brain Barrier (BBB)
  • Bi- and trispecific antibodies
  • Engineering multivalency
  • Variable domains
  • Binding specificities
  • Bi-specific T-cell engagers (BiTEs)
  • Antibody mimetics
  • Antibody-antigen binding kinetics
  • Immunogenicity
  • Effector functions

* 活动内容有可能不事先告知作更动及调整。