Cambridge Healthtech Institute's Tenth Annual

Engineering Genes and Hosts

( 基因与宿主的改变 )

Exploring Strategies in Systems Engineering and Synthetic Biology

2018年1月8日 - 9日

 

The mandate of "faster, better, less expensive" resonates with recombinant protein expression and production researchers. Thus, protein expression scientists are exploring new engineering tools including synthetic biology and systems engineering. However, many variables still must be considered during the engineering process, including verification and sequence analysis of the gene or protein of interest, codon optimization, vector construction and clone/host selection. Ultimately, as with any new system, these tools must be weighed against traditional expression and production strategies to achieve the desired quantity and quality.

Cambridge Healthtech Institute's Tenth Annual Engineering Genes and Hosts conference continues the tradition of applying effective engineering strategies for protein expression and production research leading to functional protein products. Learn from seasoned, savvy researchers as they share their real-world experiences, applications and results.

Preliminary Agenda


CRISPR ENGINEERING

FEATURED PRESENTATION:
Forward Genome Engineering

Ryan T. Gill, Ph.D., Slade Professor, Chemical and Biological Engineering, University of Colorado


CRISPR-Cas Tools for Host Cell Improvement in the Baculovirus-Insect Cell System

Donald Jarvis, Ph.D., Professor, Molecular Biology, University of Wyoming

New Strategies of CRISPR/Cas9-Based High-Throughput Functional Genomic Screening

Dongxin Zhao, Ph.D., Postdoctoral Fellow, Prashant Mali Lab, Department of Bioengineering, University of California, San Diego


CODON OPTIMIZATION

Codon and Codon Context Optimization in Synthetic Gene and Gene Library Design

Dimitris Papamichail, Ph.D., Assistant Professor, Computer Science, The College of New Jersey

Establishing Protein Production without Reinventing the Wheel: ProteinData.Cloud

Peter Nollert, Ph.D., Business Director, Research and Development, Bio Data Bridges


LIBRARY SCREENING

Mammalian Display: Antibody Discovery, Affinity Maturation and Developability Screening in IgG Format

Mike Dyson, Ph.D., CTO, IONTAS Ltd.


ENGINEERING HOSTS

Engineering Cell Factories for Protein Production

Bjorn Voldborg, Director, CHO Cell Line Development, NNF-Center for Biosustainability, Technical University of Denmark


Luncheon Presentation: A Systematic Approach to Address Development and Production Challenges for Complex Biologics

Claes Gustafsson, CCO & Founder, ATUM (formerly DNA2.0)


* 活动内容有可能不事先告知作更动及调整。