Cambridge Healthtech Institute's Eleventh Annual

Lyophilization and Emerging Drying Technologies

( 冷冻乾燥与新的乾燥技术 )

Formulation and Process Optimization, Models, QbD, Delivery and Devices

2018年1月9日 - 10日

 

The popular Eleventh Annual Lyophilization and Emerging Drying Technologies conference covers latest trends and challenges in lyophilization and emerging drying technologies. This conference will feature in-depth case studies, new and unpublished data and discussions on developing scientifically sound freeze dried formulation, process optimization for biologics and vaccines. It will also present cutting edge research and case studies on freeze/thaw and formulation challenges, drying in cartridges, storage stability, QbD and PAT approaches and strategies for scale-up from R&D scale to full production level, and selection of container closure systems. We are seeking cutting edge research findings and unpublished data to be featured at this forum.

We invite you to present a poster and attend to join with colleagues in this discussion of the key challenges and solutions in lyophilization and other drying technologies.

Preliminary Agenda


PREDICTION OF STABILITY IN FREEZE DRIED PRODUCTS: NEW TOOLS AND STRATEGIES

Hydrogen Deuterium Exchange in Lyophilized Solids: Correlation with Protein Stability

Elizabeth M. Topp, Ph.D., Dane O. Kildsig Chair and Department Head, Department of Industrial and Physical Pharmacy, Perdue University

Prediction of Protein Stability in Lyophilized Formulations: Miscibility, Mobility, and Microenvironmental pH

Eric J. Munson, Ph. D., Patrick DeLuca Endowed Professor, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky

Prediction of Degradation in Solids Using Raman Spectroscopy

Marcus T. Cicerone, Ph.D., Biomaterials Group, National Institute of Standards and Technology

New Tools for Prediction of Stability of Freeze Dried Products - A Cold Perspective

Miguel Angelo Rodrigues, Ph.D., Researcher and Invited Professor, Chemical Engineering, Instituto Superior Tecnico, University of Lisbon


MODELS AND TOOLS IN PROCESS DESIGN, SCALE UP AND TECHNOLOGY TRANSFER

Use of Model in Process Design and Scale Up

Alina Alexeenko, Ph.D., Professor, School of Aeronautics and Astronautics, Purdue University

Process Monitoring by Mass Spectrometry during Freeze Drying

Jason Stewart, B.S., Senior Associate Scientist, Pharmaceutical Research and Development, Pfizer, Inc.

Freeze-Drying of a Low Tg' and High Fill Protein Drug Product: The Critical Role of Freezing on Primary Drying Process Performance and Final Product Quality Attributes

Xiaofeng Lu, Ph.D., Principal Research Scientist, AbbVie Biotherapeutics Inc.


VISUAL INSPECTION AND RECONSTITUTION CHALLENGES

Visual Inspection and Reconstitution Challenges: Protein Aggregation and Nanobubbles

Theodore W. Randolph, Ph.D., Kenneth and Genevieve Gillespie Professor, Department of Chemical and Biological Engineering, University of Colorado, Boulder

Methods to Reduce the Reconstitution Time of High Concentration Lyophilized Protein Therapeutics

Jacob Luoma, Engineer I, Pharmaceutical Processing and Technology Development, Genentech


* 活动内容有可能不事先告知作更动及调整。