Cambridge Healthtech Institute's Eleventh Annual
Lyophilization and Emerging Drying Technologies
( 冷冻乾燥与新的乾燥技术 )
Formulation and Process Optimization, Models, QbD, Delivery and Devices
2018年1月9日 - 10日
The popular Eleventh Annual Lyophilization and Emerging Drying Technologies conference covers latest trends and challenges in lyophilization and emerging drying technologies. This conference will feature in-depth case studies, new and unpublished data and discussions on developing scientifically sound freeze dried formulation, process optimization for biologics and vaccines. It will also present cutting edge research and case studies on freeze/thaw and formulation challenges, drying in cartridges, storage stability, QbD and PAT approaches and strategies for scale-up from R&D scale to full production level, and selection of container closure systems. We are seeking cutting edge research findings and unpublished data to be featured at this forum.
We invite you to present a poster and attend to join with colleagues in this discussion of the key challenges and solutions in lyophilization and other drying technologies.
PREDICTION OF STABILITY IN FREEZE DRIED PRODUCTS: NEW TOOLS AND STRATEGIES
Hydrogen Deuterium Exchange in Lyophilized Solids: Correlation with Protein Stability
Elizabeth M. Topp, Ph.D., Dane O. Kildsig Chair and Department Head, Department of Industrial and Physical Pharmacy, Perdue University
Prediction of Protein Stability in Lyophilized Formulations: Miscibility, Mobility, and Microenvironmental pH
Eric J. Munson, Ph. D., Patrick DeLuca Endowed Professor, Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky
Prediction of Degradation in Solids Using Raman Spectroscopy
Marcus T. Cicerone, Ph.D., Biomaterials Group, National Institute of Standards and Technology
New Tools for Prediction of Stability of Freeze Dried Products - A Cold Perspective
Miguel Angelo Rodrigues, Ph.D., Researcher and Invited Professor, Chemical Engineering, Instituto Superior Tecnico, University of Lisbon
MODELS AND TOOLS IN PROCESS DESIGN, SCALE UP AND TECHNOLOGY TRANSFER
Use of Model in Process Design and Scale Up
Alina Alexeenko, Ph.D., Professor, School of Aeronautics and Astronautics, Purdue University
Process Monitoring by Mass Spectrometry during Freeze Drying
Jason Stewart, B.S., Senior Associate Scientist, Pharmaceutical Research and Development, Pfizer, Inc.
Freeze-Drying of a Low Tg' and High Fill Protein Drug Product: The Critical Role of Freezing on Primary Drying Process Performance and Final Product Quality Attributes
Xiaofeng Lu, Ph.D., Principal Research Scientist, AbbVie Biotherapeutics Inc.
VISUAL INSPECTION AND RECONSTITUTION CHALLENGES
Visual Inspection and Reconstitution Challenges: Protein Aggregation and Nanobubbles
Theodore W. Randolph, Ph.D., Kenneth and Genevieve Gillespie Professor, Department of Chemical and Biological Engineering, University of Colorado, Boulder
Methods to Reduce the Reconstitution Time of High Concentration Lyophilized Protein Therapeutics
Jacob Luoma, Engineer I, Pharmaceutical Processing and Technology Development, Genentech