Cambridge Healthtech Institute's Eleventh Annual
Lyophilization and Emerging Drying Technologies
( 冷冻乾燥与新的乾燥技术 )
Formulation and Process Optimization, Models, QbD, Delivery and Devices
2018年1月9日 - 10日
The popular Eleventh Annual Lyophilization and Emerging Drying Technologies conference covers latest trends and challenges in lyophilization and emerging drying technologies. This conference will feature in-depth case studies, new and unpublished data and discussions on developing scientifically sound freeze dried formulation, process optimization for biologics and vaccines. It will also present cutting edge research and case studies on freeze/thaw and formulation challenges, drying in cartridges, storage stability, QbD and PAT approaches and strategies for scale-up from R&D scale to full production level, and selection of container closure systems. We are seeking cutting edge research findings and unpublished data to be featured at this forum.
We invite you submit a proposal, present a poster and attend to join with colleagues in this discussion of the key challenges and solutions in lyophilization and other drying technologies.
We invite presentation proposals on the following preliminary topics:
- New research and case studies for development of challenging lyophilization processes, spray drying, crystallization and other manufacturing techniques
- Drying of new biologics and complex drug delivery systems like nanoparticles, liposomes and emulsions, etc.
- Advances in spray drying, foam drying, super critical fluid drying, microwave drying and other alternate drying technologies
- Regulatory and QbD considerations during submission for IND and BLA
- Quality by design (QbD) and PAT in freeze drying
- Use of models and tools in process design, scale-up and technology transfer
- New tools for prediction to stability of freeze dried products
- Impact of freezing, freeze thaw cycle and residual water on freeze dried protein formulation
- Advances in lyophilization technology: Controlled ice nucleation, collapse temperature, high throughput and miniaturization techniques and continuous manufacturing
- Analytical tools and novel methods for studying protein aggregation and particulates in lyophilized formulation
- Role of excipients on stability and cake structure, models and tools to characterize cake structure, protein stability
- Visual inspection and reconstitution challenges: Protein aggregation, nanobubbles
- Combination devices and delivery challenges for lyophilized products