Cambridge Healthtech Institute's Twentieth Annual

Recombinant Protein Expression and Production

( 重组蛋白质的表现与生产 )

Achieving Quality and Quantity

2018年1月9日 - 10日

 

Biopharmaceuticals currently represent the fastest-growing sector of the pharmaceutical industry, driven by a rapid expansion in the manufacture of recombinant protein-based drugs. Consequently, the efficient expression and production of these valuable biomolecules face challenges in improving their quantity and quality while minimizing time and cost. To meet these demands, an increasing variety of recombinant production platforms are being developed. Unfortunately, there is no "universal" production system which can guarantee high yields of recombinant protein, particularly as every biomolecule itself causes its own issues in terms of expression. To meet the demand, it is crucial to increase the throughput of expression, production and purification processes and systems.

Cambridge Healthtech Institute's Recombinant Protein Expression and Production conference explores the newest data and innovations relating to the best choices in hosts/systems, as well as ways to "rescue" existing systems and make them work more effectively to produce the quality and quantity of the desired biotherapeutic.

We invite presentation proposals on the following preliminary topics with an emphasis on the desired biotherapeutic protein product:

  • Matching host to protein of choice
  • Exploring novel hosts
  • Cloning strategies
  • Creation of cell banks
  • Expression in suitable systems
  • Re-engineering existing systems for better performance
  • Tuning media
  • Automation for higher throughput
  • Purification process development
  • Upstream and downstream scale-up
  • Development of analytical assays to determine identity, purity and biological activity

* 活动内容有可能不事先告知作更动及调整。