海报标题

Below is just a sample of the poster titles that will be on display at PEGS Boston 2018

 

  • Internalizing Antibody to Novel Target Expressed on Pediatric and Other Soft Tissue Tumors
  • Investigating the Effects of Pre-Existing Anti-PEG Antibodies on Mircera
  • Conditional Internalization of PEGylated Nanomedicines by PEG Engagers for Triple Negative Breast Cancer Therapy
  • Generation of Novel Anti-CLDN18.2 Monoclonal Antibodies as Therapies for Gastric and Pancreatic Cancer                           
  • Comprehensive, Efficient and Reliable Characterization of Monoclonal Antibody Aggregation by High Throughput and Quantitative Methods                                  
  • AT1412: A Patient-Derived Antibody Targeting the Tetraspanin CD9 Inhibits Tumor Progression by Stimulating the Influx of Immune Cells                                          
  • Novel Immunomodulatory Proteins Generated via Directed Evolution of Variant IgSF Domains                                     
  • Anti-FOLR1 Monoclonal Antibody Conjugate Using NexMab™ Technology                                     
  • ProTIA (Protease Triggered Immune Activator) Widens the Therapeutic Window of Bispecific T-Cell Engagers                        
  • Generation of Agonist and Antagonist Human Monoclonal Antibodies Against an Immune Checkpoint Target from the H2L2 Mouse                                      
  • Bioinformatic and Experimental Characterization of Israa, a Novel Mouse Intron-Nested Gene Involved in Regulating T-Cell Activation                                
  • Novel Transposase Tools for Cell-Line Engineering                                    
  • Fc Fusion Affimer® Biotherapeutic Targeting PD-L1 Inhibits Tumour Growth in Mouse                                             
  • Development and Characterization of a Novel Anti-IL-6R Antibody (BCD-089)                               
  • Comparison of Bridge and ACE-Format Assays for Anti-Drug Antibodies in Anti-IL-17A Treated Healthy Donors from Phase I Clinical Trial                                     
  • A Novel Bispecific Antibody to CD47/PDL1 (BCD-106)                                              
  • Identification of Adeno-Associated Virus Capsid Proteins Using ZipChip CE/MS                                            
  • Generation of Anti-Idiotypic Antibodies Against Biotherapeutics Using HuCAL                                              
  • Accelerate Kinetic Screening and Epitope Characterization of Antibody Libraries with Array SPR                                   
  • Allostery Communications in Fusion Two-Domain Proteins                                   
  • A Novel Protein Scaffold, Engineered SPINK2, for Generation of Inhibitors with High Affinity and Specificity Against Target Proteases                                     
  • Computational Driven Protein Engineering Platform Enables the Discovery and Development of Biologics with Reduced Immunogenicity                                   
  • Immunoproteogenomics for Discovering Rabbit Monoclonal Antibodies                                         
  • Combinatorial Domain Hunting (CDH) Solving Protein Production Challenges                               
  • Novel, Improved Cell-Based Assays to Enable Immunotherapy Drug Development for Checkpoint Receptors                         
  • Building Robust and Simple Cell-Based Assays for Interleukins and Their Receptors                                   
  • Anti-Human CXCR4 and Anti-Human IL-7R Antibodies Selected from Non-Immune Repertoires                                    
  • The Journey to "The" Antibody: Accessing a Versatile Toolbox                                             
  • Comparison of Manual Pipetting vs. Automated Liquid Handling Pipetting into FlowCam 8100                                      
  • Monoclonal Antibody as Therapeutics Against Emerging Infectious Diseases                                
  • Industrializing IO Therapeutic Discovery Platforms: Multispecifics, Engineered TCRs and CARs                                      
  • Enterprise Mass Spectrometry Software Solution Enabling Characterization of Biotherapeutics from Discovery and Development to Production and Quality Control                                       
  • A Novel Integrated End-to-End Workflow System Enabling Increased Throughput in Bioprocess Development
  • Automated Data Processing and Analysis for Quality Monitoring of Biotherapeutics by Multi-Attribute Method (MAM)
  • Using CHO Targeted Integration Stable Pools to Express Proteins for Research                                             
  • New Enzymatic Tools for O-Glycan Analysis Using LC-MS                                       
  • Integrated Antibody Drug Discovery: From Drug Targets to Functional Antibody Leads                                             
  • Development of an Antibody-Drug Conjugate Targeting the MUC1-C Oncoprotein on Human Cancer Cells                              
  • HPN424, a Half-Life Extended, PSMA/CD3-Specific TriTAC for the Treatment of Metastatic Prostate Cancer                            
  • Rational Engineering of Targeted Erythropoietin for Treatment of Anemia
  • Challenges and Opportunities with Early Immunogenicity Risk Assessment and Functional Testing of Immuno-Oncology Drugs
  • Discovery of Highly-Specific Claudin 6 Antibodies for Targeting Cancer                                            
  • Automated Protein Purification Using Hamilton Star with Various Wet Resins to Achieve Miniaturized Laboratory Workflow with High Consistencies                                   
  • Non-Covalent Modification of mPEGylated Nanoparticles by Humanized Bispecific Antibodies for Selective Therapy                                      
  • Development of a Protease-Activated Antibody that Reduces the Side-Effects of Rheumatoid Arthritis (RA) Therapy                                      
  • A Toolbox of Recombinant Antibodies to Study Human tRNA Synthetases in Health and Disease                                  
  • Flow Cytometric Immunophenotyping of PBMCs and Quantification of Cytokine Production from Patients in a Peptide Vaccine Study                                          
  • Tracking Media, Aggregating Assay Data, and Tracking Lineage of Expression System Samples for Bioreactor Runs, Both Individually and Across Multiple Runs                                  
  • Expanding the GS Xceed® System Vector Toolkit for Complex Recombinant Protein Expression                                    
  • Probing Antigen Recognition of Effector T Cells in Anti-Tumor Immune Responses                                     
  • An Unbiased Determination of pMHC Repertoires for Improved Antigen Prediction                                  
  • Therapeutic Antibody MS17-38 Interacts with PODXL-v2 to Define the Biomarker of Gastric Cancer                           
  • Method Development and Case Studies of Large Molecule Separations: SEC, HIC, Mixed-Mode and CE-SDS                            
  • Selection of Fully Characterized Lead Antibody Candidates by High-Throughput Multiplex Screenings                       
  • Electron Microscopy: A Powerful Tool for Characterization of Biotherapeutics                                             
  • Developing an Integrated Summary of Immunogenicity (ISI) to Effectively Manage Regulatory Risks in Product Development                                           
  • Using Peroxidases to Enhance Oxidative Folding in E. coli                                       
  • A Novel In-Vitro Human Skin Explant Test to Predict Adverse Immune Reactions to Biopharmaceuticals                                   
  • Combinatorial Screening of Yeast Displayed Libraries Using Yeast Displayed Targets                                  
  • Tolerogenic Immune Modifying Nanoparticles as an Antigen-Specific Therapy for the Treatment of Th2-Mediated Food Allergy                                              
  • Development of a mAb Binding a Conformational Epitope on Human and Rodent Insulin Receptor Using a Naive Antibody Yeast Display Library                                           
  • Selection of Monoclonal Antibodies Targeting Therapeutic Membrane Proteins Through a Cell-Based Phage Display Panning System                                       
  • Automated Particle Count Analysis to Optimize Protein Formulation to Minimize Aggregation and Perform USP 787 Subvisible Particulate Matter Testing                                     
  • PerkinElmer's ProteinEXact™ Assay for High-Throughput, High-Precision Protein Quantitation                                      
  • CEA-TCB Clinical Dose Prediction: A Mechanistic PK/PD Modeling Approach                                 
  • Development and Optimization of an Advanced Transient Expression System in CHO cells                                      
  • Reproducible MOA-Reflecting Reporter-Based Bioassays to Enable Drug Development of Biosimilars and Biobetters                                  
  • Protein Production, Kinetic Profiling and X-Ray Crystallography for Biologicals Versus Small Molecules During Early Drug Discovery - Similarities and Differences                               
  • Large Scale Study of the W-Ion Isoleucine and Leucine Determination (WILD) Method in Antibody De Novo Protein Sequencing                               
  • Enhanced Concentration Range and Sensitivity for mAb Structural Characterization Using Microfluidic Modulation Spectroscopy (MMS)                                             
  • Monitoring Critical Quality Attributes Supporting Development of Biologics                                  
  • A Candidate Triage Roadmap: Upfront Affinity and Cross-Reactivity Data Dovetailed with Sequence Diversity and Computational Modeling Reduce Reconstruction Workload                                 
  • Artificial Chaperone Technology for Conformational Diseases                                             
  • A Polar Sulfamide Spacer Significantly Enhances the Manufacturability, Stability, and Therapeutic Index of Antibody-Drug Conjugates                                  
  • Flexible Multivalent Antibody Development Platform Based on Human Heavy Chain Antibodies                                  
  • Optimizing Small Scale Devices for CHO and HEK293                                
  • Vectorization in an Oncolytic Vaccinia Virus of Antibodies Against Programmed Cell Death -1 (PD-1) Allows Their Intratumoral Delivery and an Improved Tumor-Growth Inhibition                                     
  • Polymeric Hydrogels as Drug Delivery Systems for Recombinant Anti-Human KLK7                                     
  • Discovery of Protease Inhibitory mAbs                                          
  • Functional Interrogation and Mining of Natively Paired Human VH:VL Libraries                                            
  • Metabolic Incorporation of a Fluorescent Amino Acid into Proteins of Interest for Live-Cell Imaging                           
  • A Structure-Based Platform for the Design of Next-Generation TCR Therapeutics                                       
  • Proximity-Based Sortase-Mediated Ligation                                
  • Optimization for Heterologous Disulfide Bonded Protein Manufacture: Production of Antibody Fragments in the Periplasm and Cytoplasm of E. coli                                   
  • Discovery of New Antibodies That Target and Transport the Blood-Brain Barrier                                          
  • Characterization of USP Oligosaccharide System Suitability Mixture A and Mixture B Reference Standards                             
  • Use of Mammalian Virus Display to Select Antibodies Specific for Complex Membrane Antigens                                 
  • Monitoring the Critical Quality Attributes of Antibody Drug Conjugates (ADCs) as Part of Biosimilar Development: Case Studies of Ado-Trastuzumab Emtansine                                             
  • A Novel Phenyl-Based RPLC Stationary Phase for High Throughput, High Resolution Characterization of Protein Therapeutics                                             
  • An Efficient Method for the Determination of Trace Excipient Impurities in Biotherapeutic Drug Products Containing Polysorbate                                        
  • xCella Microcapillary Platform Enables High-Throughput Functional Screening of Antibody Libraries                           
  • YUMAB - Custom-Made Natural and Fully Human Antibodies for Diagnostics and Therapy: A Case Study                                  
  • Development of a Novel "Imbalanced" CD20/CD3 Bispecific Antibody by Computational Design                                   
  • Site-Selective Chemical Conjugation of Antibodies                                   
  • Fc Binding and Function Assays: Towards Understanding the Mechanism of Action of Therapeutic Antibodies                        
  • Abdurin Drug Conjugates: Small in Size and Long Half-Life to Improve Drug Concentrations in the Target Tissue                                       
  • Growing Portfolio of Modular Binders for the Rapid Generation of Bispecific Antibodies                                         
  • Rational Design of Immuno-Oncology Biologics with Improved Safety and Efficacy                                     
  • Designing Bispecific Antibodies for Immuno-Oncology                                           
  • A Chemo-Enzymatically Linked AT1413 T-Cell Engaging Antibody Targeting a Unique Sialylated Epitope on CD43 Present in Acute Myeloid Leukemia and Melanoma                                 
  • Engineering of ProTIAs: Bispecific Pro-Drugs for the Treatment of Solid Malignancies                                
  • A Rapid, High-Throughput Recombinant Antibody Expression System for Therapeutic Antibody Discovery and Validation                                   
  • A Study in Light Scattering Techniques to Investigate Protein Stability and Aggregation                                            
  • HERA-GITRL: A Novel Hexavalent Human GITR Agonist Promoting Anti-Cancer Immunity by Enhancing T Cell Activation                                   
  • Quantitative Systems Pharmacology and Immunotherapy: Accelerating Lead Generation and Optimization of a PD-1 x TIM-3 Biotherapeutic in Immuno-Oncology                                          
  • Screening, Optimization and Characterization of a Novel 4-1BB x 5T4 ADAPTIR Bispecific Antibody                           
  • Machine Learning for Predictive Antibody Design and Humanization                                
  • A Platform Technology for the Rapid Generation of Robust Anti-Idiotypic Binders for Clinical PK Assays                                    
  • Affimer® Reagents Facilitate Affinity Chromatography Purification of IgG                                       
  • High Throughput Protein Expression, Purification, and Testing - Substantially Increasing the Discovery Rate of Novel, Active Proteins                                           
  • Label-Free Detection of High-Density Peptide Arrays                               
  • Development and Characterization of a Human Anti-PCSK9 Antibody (BCD-096)                                         
  • Assay Development and Validation for Detecting NAbs Against MAB-Against-IL17A in Human Serum                         
  • Novel Anti-CD20 Antibody: Development, Characterization and Preclinical Studies                                    
  • Development and Characterization of a Novel Bispecific Biparatopic Anti-Her2 Antibody                                        
  • Comparison of Immunogenicity Test Methods Destined for Clinical Studies of Monoclonal Anti-CTLA4 Antibody                                       
  • BENDER: First Semantic-Based Antibody Folding with Structural Annotations                                
  • Development and Qualification of a High Performance Liquid Chromatography Method for Monitoring Triton X-100 During the Purification Process Development of a Biopharmaceutical                                      
  • CAT-02-106, a Site-Specifically Conjugated Anti-CD22 Antibody Bearing an MDR1-Resistant Maytansine Payload, Yields Excellent Efficacy and Safety in Preclinical Models                                       
  • A Nanobody Directed Against the Spot-Tag, a Novel Peptide Tag for Protein Detection, Purification, and Imaging                                       
  • The Effect of Signal Peptide on a Protein Expression and Secretion                                    
  • Two-Dimensional Liquid Chromatography (2D-LC), Resolution to Exosome Characterization in Cell Culture Media                                       
  • Roles of Active-Site Aromatic Residues in Temperature Adaptation of Serine Esterases                                            
  • Development of Anti-Globo H ADC                                  
  • Novel Excipients for Liquid Stabilization of Antibody-Derived Pharmaceuticals and Suggested Mechanism for Protection from Aggregation                                              
  • SMART Libraries and Phage-Induced Directed Evolution of Cas9 to Engineer Reduced Off-Target Activity                                 
  • Benchmarking the Immunoinformatic Tools for the Alignment and Annotation of Antibody Repertoire Sequencing Data                                              
  • Driving Robust and Reproducible ADCC and T Cell Redirection with Single-Donor Derived KILR® CD16 Effector Cells                                       
  • Ready-to-Use Potency Assays for Bevacizumab, Aflibercept, and Ranibizumab                                             
  • Static Light Scattering Signatures Used to Identify Stability and Minimize Aggregation During Formulation Development                                           
  • FlowCam Nano Provides Counts, Sizes and Images of Nano- and Microparticles: Application to a Therapeutic Protein Pumping Study                                         
  • The Benefits of Bispecific mAb-square Antibodies Targeting EGFR and HGF                                   
  • A Bispecific Multivalent HIV-1 Neutralizing Antibody Potently Suppresses SHIV Infection                                        
  • Flow Chemistry Conjugation of a Native Antibody - Kinetic Control of Antibody-Enzyme Ratio                               
  • First-in-Class Expression and Characterization Request Management System to Increase Biotherapeutics Research and Development Operational Efficiency                                      
  • Large-Scale Determination of Affinity, Specificity, and Kinetics of Complex Molecules: Automating Data Analysis at Pace with the New Possibilities                                         
  • Deep Learning Enables Easy Switching of HCS Modalities, From Small to Large Molecules and Between Human Donors                                        
  • Automated Intact Mass Analysis for the Characterization of Antibodies                                          
  • Tunably Stable-Acid Clevable Trityl Linker                                     
  • A High Throughput Approach to Construct Generation, Expression Screening and Sample Management for Recombinant Protein Production                                     
  • Aggregation-Based High-Throughput Screen Identifies New Leads for Myocilin-Glaucoma Therapeutics                                   
  • Implementation of Automated Workflows to Cell Line Development Processes                                           
  • HORIZON - High Throughput Low Volume Subvisible Particle Analysis                                              
  • Engineering Posttranslational Proofreading to Discriminate Nonstandard Amino Acids                                             
  • Bi-Specific Soluble T Cell Receptors Targeting Cancer, Infectious and Autoimmune Diseases                                  
  • ImmTAC™ - Engineering High-Affinity, Soluble TCRs                                 
  • A Toolbox of Functional Assays to Accelerate Immuno Oncology Drug Development                                 
  • High-Resolution Epitope Mapping and Specificity Profiling of mAbs Targeting Complex Proteins                                  
  • A Bispecific Approach for the Selective Elimination of Tumor Tregs                                   
  • Multispecific and Multivalent Antibodies as OX40 Agonists                                   
  • Increasing Protein Yields Through the Optimization of High Density Transient Mammalian Expression                       
  • Using Anti-Poly (Ethylene Glycol) Bioparticle for the Quantitation of PEGylated Nanoparticles                                      
  • Auto-Grafted Hinge Domain as Universal Ab Lock to Enhance the Selectivity by Structure-Based Computational Methods                                    
  • The Making of Antibody Like (T) Cell Engager on the Basis of VH-VL Heterodimer Formation and its Application in Cancer Therapy                                       
  • Modulating Receptor Signaling Using Variabody: A Novel Bispecific Antibody Format Enables One-Pot Synthesis of Fab-Dimer Library                                   
  • Secure and Traceable Acoustic Liquid Handling - An Integrated System for Regulated Laboratory Environments                                       
  • Characterization of Potent TIGIT-Specific Antibodies Derived from Very Diverse Phage Display Libraries                                   
  • The Tub-tag®: A Tool for Site-Specific Protein Conjugation with Application in Antibody-Drug-Conjugate (ADC) Development                                           
  • Isolation of Functionally Unaffected Cells Straight from Buffy Coat, LRSC or Leukopak Without Density Gradients                                       
  • ProPOSE: A Direct-Search Protein-Protein Docking Algorithm - Comparative Assessment to Commonly Used Methods                                    
  • Prediction of Antibody-Drug Conjugate Site Occupancies at Lysine Residues                                 
  • Thermostable Ferritin as a Cage Confinement Chaperone to Fold and Stabilize Inclusion Body Proteins                                     
  • Anthracycline-Based Antibody-Drug Conjugates with Potent Immune-Stimulatory Functions                                
  • Maximising Value in Early Development                                       
  • A Novel In-Vitro Assay for Detection of Immunotoxicity of Aggregated Monoclonal Antibodies                                     
  • High Throughput Analysis of Antibody Glycans in Cell Culture Samples                                            
  • Enzymatic (Dual) Site-Specific Conjugation of Engineered and Native Antibodies                                         
  • High Resolution Epitope Mapping and Antibody Cross-Reactivity Analysis                                      
  • A mCD3xP-Cadherin Mouse Bispecific Allows Immune Profiling of T Cell and Myeloid Cell Populations During Treatment of Syngeneic Mouse Tumor Models                                          
  • FTIR Spectroscopy as a Tool for the Secondary Structure Characterization of Protein Therapeutics                              
  • The Journey of Mylotarg™ from Discovery to Regulatory Approval                                    
  • Thermal Denaturation Analysis of Bovine Serum Albumin by Microfluidic Modulation Spectroscopy                          
  • Efficient and Consistent Transient Protein Production Using a High Quality Ready-to-Use PEI                                
  • A Multi-Assay Approach to Evaluate the Mode of Action and Determine Equivalence Potency of a Biosimilar Drug                                       
  • Releasing the Brakes: Quantitative Cell-Based Bioassays to Advance Individual or Combination Immune Checkpoint Immunotherapy                                      
  • Improved T Cell Activation Bioassays to Advance the Development of Bispecific Antibodies and Engineered T Cell Immunotherapies                                  
  • Measurement of Fc-Mediated ADCC and CDC Activity of Anti-TNFα and Anti-VEGF Therapeutic Antibodies Using Reporter-Based Bioassays and Engineered TNFα+ and VEGF+ Target Cells                                      
  • Solution Based Homogeneous Immunoassays for Characterization and Screening of Antibody-FcRn Interactions                                       
  • Hitting the Gas: Quantitative Cell-Based Bioassays to Advance Immunotherapy Programs Targeting Co-Stimulatory Immune Checkpoint Receptors                                         
  • ProtaBank: A Comprehensive Database for Protein Engineering and Design                                  
  • Studying the Prevalence of Secondary Light Chains in Research Purpose Monoclonal Antibodies with MS-Based De Novo Protein Sequencing                                    
  • HOS Study for IgG Samples Spiked with Different Amount of BSA by MMS                                     
  • Multivariate Analysis of Formulation and Molecular Attributes on Monoclonal Antibody Absorption upon Subcutaneous Administration                                           
  • Evaluation of New Technology for Quality Control Laboratories: Microchip Capillary Electrophoresis                         
  • Confirming Target Specificity or Revealing Off-Target Binding Using Human Plasma Membrane Protein Arrays                                       
  • Evaluation of Variable Pathlength Ultra-Violet Spectroscopy for Determination of Protein Concentration in Active Pharmaceutical Ingredient Solutions                                              
  • The Contorsbody: Design, Structure, Function                                            
  • Integrated Approaches Enabled Rapid and Sensitive Characterization of Functional CD73 Antibodies with Differentiating Mechanisms of Binding and Inhibition                                             
  • Rediscover the Strengths of Your PA 800 Plus - A Multi Attribute Protein Analyzer                                    
  • In Vivo Assessment of the Immunogenicity and Anaphylactic Reactivity of PEGylated Nano-Biopharmaceuticals in Pigs                               
  • Artificial Chaperone Technology to Enhance the Production of "Difficult-to-Express Proteins"                               
  • Expression and Bioengineering of Granzyme B-Based ADC                                    
  • GlycoConnect™ and HydraSpace™ Technologies One Step from the Clinic: Decomposition of Parameters Contributing to the Improved Therapeutic Index                                      
  • Selection Technology Using Bacteriocin-Immunity to Improve Microbial Fermentation                                            
  • Sensitivity Enhancement in Immunoassays by Polymeric Protein G                                    
  • Rapid Purification and Characterization of Recombinant Proteins and Antibodies: Capturem High-Capacity Membranes                                              
  • Development of a Fully Human T-Cell Engaging Bispecific Antibody for the Treatment of Multiple Myeloma                           
  • Streamlined Bi-Specific Antibody Production Using Automated Chemoenzymatic Site-Specific Crosslinking                             
  • Directed Evolution of Anti-OCT4A ABfinity Rabbit Recombinant Monoclonal Antibody CDRs to Enhance Sensitivity                                       
  • Strategies for High-Titer Protein Expression Using the ExpiCHO and Expi293 Transient Expression Systems                             
  • Improved Protein Impurity Analysis by Simple Fluorescent Labeling and Capillary Electrophoresis                               
  • ExpiSf: A Chemically-Defined Baculovirus-Based Expression System for Enhanced Protein Production in Sf9 Cells                                       
  • New Innovation: Harvesting CHO and HEK293 Cells with the Rapid Clear® Cap Provides 0.2µm Filtration in a Fraction of the Time and Requiring Less Consumables than Other Clarification Methods                                         
  • Simplified Sample Prep of Antibodies for Purity Determination by SEC-HPLC Using the Thomson Filter Vials                            
  • Directed Evolution of CRISPR-Cas9 to Increase Its Specificity                                 
  • Simultaneous Improvement of Specific Catalytic Activity and Thermal Stability of MBP Fusion Heaprinase II by Modifying Amino Acid Residues in 758 Site                                  
  • A New Twist on Antibody Library Engineering                                             
  • Increasing Antibody Reagent Throughput and Titre to Meet Project and Timeline Demands                                   
  • Degradation in Co-Formulation of Therapeutic Proteins                                         
  • Simple Antibody Modification Boosts ADC Efficacy Against Poorly-Internalizing or Poorly-Expressing Cancer Cell Targets                                        
  • On the Use of Chaperonin Biosensors to Capture Preaggregation States of Biotherapeutics                                   
  • An In Vivo Platform to Select and Evolve Aggregation-Resistant Protein Therapeutics                               
  • Assessing the Aggregation Propensity of Clinically Relevant mAbs Using Extensional Flow                                       
  • Development of a Simple, Rapid and Sensitive Homogeneous Immunoassay                                
  • Human Cell Line Shows Better Expression Level for Recombinant Factor VII Production                                           
  • Evaluation of Different Culture Parameters for an Efficient CAR-T Cells Production                                     
  • Determining the Relationship Between T Cell Response and Affinity of Cytomegalovirus-Specific TCRs                                      
  • Concisely Produced Homogeneous Antibody-Drug Conjugates by A Tryptophan-Selective Protein Bioconjugation                                       
  • Uncovering the Structural Basis for Antibody Recognition of SAS1B                                   
  • Quality Comparison of Biosimilar and Copy Filgrastim Products with the Innovator Product                                   
  • Rapid Protein Production in CHO Cells: From Transfection to 100g in 6 Weeks                                             
  • Investigating the Effects of Pre-Existing Anti-PEG Antibodies on Mircera                                         
  • Computational Driven Protein Engineering Platform Enables the Discovery and Development of Biologics with Reduced Immunogenicity                                   
  • Monoclonal Antibody as Therapeutics Against Emerging Infectious Diseases                                
  • Rational Engineering of Targeted Erythropoietin for Treatment of Anemia                                     
  • A Toolbox of Recombinant Antibodies to Study Human tRNA Synthetases in Health and Disease                                  
  • Probing Antigen Recognition of Effector T Cells in Anti-Tumor Immune Responses                                     
  • An Unbiased Determination of pMHC Repertoires for Improved Antigen Prediction                                  
  • A Novel In-Vitro Human Skin Explant Test to Predict Adverse Immune Reactions to Biopharmaceuticals                                   
  • Combinatorial Screening of Yeast Displayed Libraries Using Yeast Displayed Targets                                  
  • Metabolic Incorporation of a Fluorescent Amino Acid into Proteins of Interest for Live-Cell Imaging                           
  • Proximity-Based Sortase-Mediated Ligation                                
  • Discovery of New Antibodies That Target and Transport the Blood-Brain Barrier                                          
  • Benchmarking the Immunoinformatic Tools for the Alignment and Annotation of Antibody Repertoire Sequencing Data                                              
  • A Bispecific Multivalent HIV-1 Neutralizing Antibody Potently Suppresses SHIV Infection                                        
  • The Making of Antibody Like (T) Cell Engager on the Basis of VH-VL Heterodimer Formation and its Application in Cancer Therapy                                       
  • Thermostable Ferritin as a Cage Confinement Chaperone to Fold and Stabilize Inclusion Body Proteins                                     
  • A Novel In-Vitro Assay for Detection of Immunotoxicity of Aggregated Monoclonal Antibodies                                     
  • An In Vivo Platform to Select and Evolve Aggregation-Resistant Protein Therapeutics                               
  • Assessing the Aggregation Propensity of Clinically Relevant mAbs Using Extensional Flow                                       
  • Human Cell Line Shows Better Expression Level for Recombinant Factor VII Production                                           
  • Evaluation of Different Culture Parameters for an Efficient CAR-T Cells Production                 
  • Determining the Relationship Between T Cell Response and Affinity of Cytomegalovirus-Specific TCRs
  • Uncovering the Structural Basis for Antibody Recognition of SAS1B
  • Quality Comparison of Biosimilar and Copy Filgrastim Products with the Innovator Product
  • CANscript Is an Ex Vivo Human Tumor Culture Platform Capable of Accurately Capturing Response to Immune Modifying Agents

 

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