回归生物学：免疫疗法的精确性与进步的融合

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Bi & Multispecific Engineering
双特异性/多特异性工程

Nanobody applications to bi and multispecifics
奈米抗体在双特异性/多特异性中的应用
Creating functional bispecifics and multispecifics
创建功能性双特异性和多特异性
Target selection
目标选择
Engineering bi/multispecifics for solid tumors
实体肿瘤的双特异性/多特异性工程

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Translating Multispecific Success
成功转化多特异性

Combining multispecifics with cellular modalities
结合多特异性和细胞模式
ML and data in bi/multispecific development
双特异性/多特异性开发中的机器学习与数据
Addressing safety and regulatory hurdles
解决安全性和监管上的挑战
Learnings from solid tumor clinical successes
实体肿瘤临床结果的经验教训

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Antibody-Drug Conjugates
ADC（抗体药物偶联物）

Improvements in linker technologies
提升连结器技术
Site-specific conjugation
位点特异性偶联
Addressing resistance and toxicity to improve therapeutic indexes
解决抗药性和毒性问题以改善治疗指标
Enhancing solid tumor targeting and specificity for better efficacy
增强实体肿瘤的标靶性和特异性，提高疗效

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Breakthroughs in Cell Therapy
细胞疗法的突破

CAR T therapy
CAR T 疗法
TILs, TCRs, Tregs for solid tumor indications
用于实体癌适应症的 TIL、TCR、Treg
Combining multiple cell therapies together
结合多种细胞疗法
Lowering attrition rate in the clinic
降低临床上的停药率

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Autoimmunity
自体免疫

Learnings from IO applied to autoimmunity
将IO的经验应用于自体免疫
B cell targeting
B细胞靶向
Understanding the autoimmunity microenvironment
了解自体免疫微环境
Transient approaches
过渡方法

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Innate Immunity
先天免疫

Understanding solid tumor biology
了解实体瘤生物学
NK cell engagers and gamma delta developments
NK 细胞接合子和γ δ 的开发
ML and data science applications
ML 和数据科学的应用
Translatable models
可翻译模型

目錄下載 (PDF)

目錄下載(PDF)