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17th Lab-on-a-Chip and Microfluidics World Congress 2024

培训课程

Microfluidics and Nanofluidics for Diagnostic Tests

2024年11月18日 09:00-11:00 -- Held at The Slate Room, The Hills Hotel, Laguna Hills, California

In vitro diagnostic testing is projected to be a $150B market in 2032 and has been driven by the new push in precision medicine, which seeks to match a patient’s molecular composition of his/her disease to the therapy that would maximize favorable outcomes for that patient. However, the complexity of most molecular testing strategies has demanded new paradigms to streamline the workflow and alleviate the need for sophisticated equipment and well-trained operators to carry out the diagnostic test. In this training course, I will cover the challenges and opportunities for both microfluidics and nanofluidics for clinical diagnostic testing.

The specific items that will be covered in this training course include the following:
1. Different types of clinical tests to manage a particular disease.
2. Clinical and analytical figures-of-merit requirements in clinical diagnostics.
3. Use of liquid biopsy markers for cancer disease management.
4. Current diagnostic tests for cancer management.

Microfluidics for clinical testing.
a. Test requirements.
b. Logical choice - plastic microfluidics.
c. Survey of microfluidic devices for clinical sample processing

PCR
1. Conventional PCR (thermal cycling)
2. Droplet digital PCR
3. Isothermal amplification
4. Mutation detection assays
5. Ligase detection reactions
6. Allele specific PCR

Device examples for liquid biopsy analysis
1. Enrichment of CTCs
2. Enrichment of EVs

Commercial systems
1. Bio-Rad ddPCR
2. Agilent TapeStation

Integrated systems for clinical sample processing.
1. Different types of integrated systems.
2. Examples of integrated systems for processing liquid biopsy samples.

Nanofluidics: the wave of the future for clinical testing.
1. What is nanofluidics and what can it offer.
2. How to make nanofluidic devices - differences compared to microfluidics
3. Logical choice - plastic-based nanofluidics
4. Examples of nanofluidics in medical diagnostics
5. Nanopore sequencing
6. DNA stretching for the detection of DNA structural variations.

**Slide Decks of all Material Presented will be Available via PDF Files Electronically to All Training Course Participants**

Steve Soper, Foundation Distinguished Professor; Director, Center of BioModular Multi-scale System for Precision Medicine, Adjunct Professor, Ulsan National Institute of Science & Technology, The University of Kansas

Microfluidic Product Development: How to Integrate Design for Manufacture Benchtop to Commercial Scale

2024年11月18日 11:00-13:00 -- Held at The Slate Room, The Hills Hotel, Laguna Hills, California

This training course is being taught by Dr. Leanna Levine, a veteran in the microfluidics, system design and product development space. The goal of this training course is to present an actionable set of tools for translating microfluidic design into products.

Specifically, the following topics will be addressed:

Looking at product development from the view point of your stakeholder
Create milestones with deliverables that de-risk and build momentum
Benchmark your results to assure data integrity; good science is necessary for a viable product
When to transition from a working alpha to a beta prototype
Understand and balance function and complexity to avoid a high cost of manufacture

The overall goal of this training course is to engage with fellow attendees, engage with the instructor and discuss topics as they relate to your product development efforts. Subsequent to this course is the 2.5-day main conference and a deep dive into these areas during the conference in presentations and discussions.

**If you are involved in microfluidic product development, this training course is a must-attend**

Leanna Levine, Founder & CEO, ALine, Inc.

3D-Printing of Microfluidics

2024年11月18日 20:30-22:30 -- Held at The Slate Room, The Hills Hotel, Laguna Hills, California

3D printing has been gaining popularity as a method for rapidly producing microfluidic devices with complex channel structures routed in three dimensions.

This short course will cover:

Mechanisms of 3D printing techniques as applied to microfluidic fabrication,

The state of the art of commercially available solutions for microfluidic printing

Applications and limitations of 3D-printed microfluidic systems

How emerging and future technologies will improve the potential of 3D printing as a microfluidic fabrication tool

Noah Malmstadt, Professor of Chemical Engineering and Materials Science, University of Southern California

Introduction to Microfluidics

2024年11月19日 20:30-22:30 -- Held at The Slate Room, The Hills Hotel, Laguna Hills, California

Introduction to Microfluidics Training Course

**A Training Course for Beginners and New Entrants into the Microfluidics Field**

This presentation will introduce basics of microfluidics.

• Topics include size scales of microfluidic devices and how that affect microscale fluid flows
• The evolution and different methods of microfluidic device fabrication
• Select biological applications including cellular, molecular, and exosome applications
• Some of the challenges and opportunities and future perspectives will also be discussed
• Time will also be reserved for questions and discussions

**This is an excellent course for new entrants seeking an immersion into the microfluidics field -- the course is taught by Professor Shu Takayama, a World Leader in the Lab-on-a-Chip and Microfluidics Field.**

Shuichi Takayama, Professor, Georgia Research Alliance Eminent Scholar, Georgia Institute of Technology & Emory University School of Medicine

* 活动内容有可能不事先告知作更动及调整。